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  • Understanding the molecular dynamics of type-2 diabetes drug target DPP-4 and its interaction with Sitagliptin and inhibitor Diprotin-A.

Understanding the molecular dynamics of type-2 diabetes drug target DPP-4 and its interaction with Sitagliptin and inhibitor Diprotin-A.

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2014 Nov Others C Chakraborty, MJ Hsu, G Agoramoorthy - Cell biochemistry and …, 2014 - Springer

Full Author : ['Chakraborty, Chiranjib', 'Hsu, Minna J', 'Agoramoorthy, Govindasamy']
Journal Title : Cell biochemistry and biophysics
Chapter : Section3
Journal Year : 2014
Cited by : 22.0

The occurrence of type 2 diabetes (T2D) accounts for 90-95 % of all diabetes. Intestine hormone glucagon-like peptide-1 (GLP-1) has an antidiabetic role that enhances insulin secretion and pancreatic beta-cell proliferation. GLP-1 is degraded by the enzym..... Read More

Keywords : ["diabetes drug target", "molecular dynamic", "inhibitor diprotina", "understand", "sitagliptin", "interaction"]
PubMed Link : https://link.springer.com/article/10.1007/s12013-014-9998-0
Google Scholar Link : https://scholar.google.com/scholar?cites=6199522234125476374&as_sdt=2005&sciodt=0,5&hl=en&num=20