Trigonelline and diosgenin attenuate ER stress, oxidative stress-mediated damage in pancreas and enhance adipose tissue PPARgamma activity in type 2 diabetic rats.

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2014 Nov Others M Tharaheswari, N Jayachandra Reddy… - Molecular and cellular …, 2014 - Springer 97

Full Author : ['Tharaheswari, M', 'Jayachandra Reddy, N', 'Kumar, R', 'Varshney, K C', 'Kannan, M', 'Sudha Rani, S']
Journal Title : Molecular and cellular biochemistry
Chapter : Section3
Journal Year : 2014
Cited by : 94.0

Type 2 Diabetes mellitus (T2DM) is characterized by peripheral insulin resistance, impaired insulin secretion, and reduced beta-cell mass. Mechanisms that underlie beta-cell failure include glucotoxicity, lipotoxicity, endoplasmic reticulum (ER) stress, a..... Read More

Keywords : ["diosgenin attenuate er stress oxidative stressmediate damage", "enhance adipose tissue ppargamma activity", "type diabetic rat", "trigonelline", "pancrea"]
PubMed Link : https://link.springer.com/article/10.1007/s11010-014-2152-x
Google Scholar Link : https://scholar.google.com/scholar?cites=2278725500580925510&as_sdt=80005&sciodt=0,11&hl=en&num=20

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Trigonelline and diosgenin attenuate ER stress, oxidative stress-mediated damage in pancreas and enhance adipose tissue PPARgamma activity in type 2 diabetic rats.