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  • Metformin attenuates effects of cyclophilin A on macrophages, reduces lipid uptake and secretion of cytokines by repressing decreased AMPK activity.

Metformin attenuates effects of cyclophilin A on macrophages, reduces lipid uptake and secretion of cytokines by repressing decreased AMPK activity.

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2018 Mar 30 Others S Ramachandran, V Anandan, VR Kutty… - Clinical …, 2018 - portlandpress.com

Full Author : ['Ramachandran, Surya', 'Anandan, Vinitha', 'Kutty, V R', 'Mullasari, Ajit', 'Pillai, M Radhakrishna', 'Kartha, Cheranellore Chandrasekharan']
Journal Title : Clinical science (London, England : 1979)
Chapter : Section3
Journal Year : 2018
Cited by : 11.0

Growing evidence implicates cyclophilin A secreted by vascular wall cells and monocytes as a key mediator in atherosclerosis. Cyclophilin A in addition to its proliferative effects, during hyperglycemic conditions, increases lipid uptake in macrophages by..... Read More

Keywords : ["repress decrease ampk activity", "macrophage reduce lipid uptake", "metformin attenuate effect", "secretion", "cytokine", "cyclophilin"]
PubMed Link : https://portlandpress.com/clinsci/article-abstract/132/6/719/72165
Google Scholar Link : https://scholar.google.com/scholar?cites=7809003940484738459&as_sdt=5,26&sciodt=0,26&hl=en&num=20