RSSDI Repository, Complications of Diabetes Demonstration RSSDI Repository, Complications of Diabetes Demonstration

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Uromodulin rs4293393 T>C variation is associated with kidney disease in patients with type 2 diabetes.

BACKGROUND & OBJECTIVES: Uromodulin, a UMOD gene encoded glycoprotein is synthesized exclusively in renal tubular cells and released into urine. Mutations lead to uromodulin misfolding and retention in the kidney, where it might stimulate cells of immune ..... Read More