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  • In silico identification and wet lab validation of novel cryptic B cell epitopes in ZnT8 zinc transporter autoantigen.

In silico identification and wet lab validation of novel cryptic B cell epitopes in ZnT8 zinc transporter autoantigen.

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2019 Apr 15 Others S Shruthi, V Mohan, MR Maradana… - International journal of …, 2019 - Elsevier

Full Author : ['Shruthi, Sugumar', 'Mohan, Viswanathan', 'Maradana, Muralidhara Rao', 'Aravindhan, Vivekanandhan']
Journal Title : International journal of biological macromolecules
Chapter : Section3
Journal Year : 2019
Cited by : 1.0

Zinc transporter 8 (ZnT8) is a novel immunodominant autoantigen, associated with Type-1 diabetes. A non-synonymous polymorphism (R325W) in its gene is associated with Type-2 diabetes. In this study, we performed an in silico B cell epitope prediction foll..... Read More

Keywords : ["novel cryptic b cell epitope", "zinc transporter autoantigen", "wet lab validation", "silico identification"]
PubMed Link : https://www.sciencedirect.com/science/article/pii/S0141813018365103
Google Scholar Link : https://scholar.google.com/scholar?cites=3600619607994111680&as_sdt=2005&sciodt=0,5&hl=en&num=20