Azadirachtin inhibits amyloid formation, disaggregates pre-formed fibrils and protects pancreatic beta-cells from human islet amyloid polypeptide/amylin-induced cytotoxicity.

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2019 Mar 15 Others R Dubey, K Patil, SC Dantu, DM Sardesai… - Biochemical …, 2019 - portlandpress.com 81

Full Author : ['Dubey, Richa', 'Patil, Ketaki', 'Dantu, Sarath C', 'Sardesai, Devika M', 'Bhatia, Parnika', 'Malik, Nikita', 'Acharya, Jhankar D', 'Sarkar, Soham', 'Ghosh, Soumadwip', 'Chakrabarti, Rajarshi', 'Sharma, Shilpy', 'Kumar, Ashutosh']
Journal Title : The Biochemical journal
Chapter : Section3
Journal Year : 2019
Cited by : 23.0

The human islet amyloid polypeptide (hIAPP) or amylin is the major constituent of amyloidogenic aggregates found in pancreatic islets of type 2 diabetic patients that have been associated with beta-cell dysfunction and/or death associated with type 2 diab..... Read More

Keywords : ["azadirachtin inhibit amyloid formation disaggregate preform fibril", "human islet amyloid polypeptideamylininduce cytotoxicity", "protect pancreatic betacell"]
PubMed Link : https://portlandpress.com/biochemj/article-abstract/476/5/889/219542
Google Scholar Link : https://scholar.google.com/scholar?cites=5993989929293643059&as_sdt=80005&sciodt=0,11&hl=en&num=20

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Azadirachtin inhibits amyloid formation, disaggregates pre-formed fibrils and protects pancreatic beta-cells from human islet amyloid polypeptide/amylin-induced cytotoxicity.