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  • The -866G/A polymorphism in the promoter of the UCP2 gene is associated with risk for type 2 diabetes and with decreased insulin levels.

The -866G/A polymorphism in the promoter of the UCP2 gene is associated with risk for type 2 diabetes and with decreased insulin levels.

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2019 Jun 15 Others P Gomathi, AP Samarth, NBAJ Raj, S Sasikumar… - Gene, 2019 - Elsevier

Full Author : ['Gomathi, Panneerselvam', 'Samarth, Apurwa P', 'Raj, Nancy Bright Arul Joseph', 'Sasikumar, Sundaresan', 'Murugan, Ponniah Senthil', 'Nallaperumal, Sivagnanam', 'Selvam, Govindan Sadasivam']
Journal Title : Gene
Chapter : Section3
Journal Year : 2019
Cited by : 12.0

BACKGROUND AND AIM: Oxidative stress and impaired insulin secretion is an underlying major risk factor for the development of type 2 diabetes (T2D). Uncoupling protein-2 (UCP2) is involved in the regulation of reactive oxygen species production, insulin s..... Read More

Keywords : ["decrease insulin level", "type diabetes", "risk", "promoter", "polymorphism", "gene", "associate"]
PubMed Link : https://www.sciencedirect.com/science/article/pii/S0378111919303038
Google Scholar Link : https://scholar.google.com/scholar?cites=4898639911587931332&as_sdt=5,33&sciodt=0,33&hl=en&num=20