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  • Role of DNA-LL37 complexes in the activation of plasmacytoid dendritic cells and monocytes in subjects with type 1 diabetes.

Role of DNA-LL37 complexes in the activation of plasmacytoid dendritic cells and monocytes in subjects with type 1 diabetes.

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2020 Jun 1 Others D Badal, D Dayal, G Singh, N Sachdeva - Scientific Reports, 2020 - nature.com

Full Author : ['Badal, Darshan', 'Dayal, Devi', 'Singh, Gunjan', 'Sachdeva, Naresh']
Journal Title : Scientific reports
Chapter : Section3
Journal Year : 2020
Cited by : 7.0

Initiation of type 1 diabetes (T1D) is marked by the infiltration of plasmacytoid dendritic cells (pDCs) and monocytes in pancreatic islets. Dying beta cells release self-DNA, which forms complexes with antimicrobial peptide, LL37, and its delayed clearan..... Read More

Keywords : ["plasmacytoid dendritic cell", "type diabetes", "subject", "role", "monocyte", "complex", "activation"]
PubMed Link : https://www.nature.com/articles/s41598-020-65851-y
Google Scholar Link : https://scholar.google.com/scholar?cites=15142086494458824540&as_sdt=80005&sciodt=0,11&hl=en&num=20