Implication of altered ubiquitin-proteasome system and ER stress in the muscle atrophy of diabetic rats.
BACKGROUND: Skeletal muscle is adversely affected in type-1 diabetes, and excessively stimulated ubiquitin-proteasome system (UPS) was found to be a leading cause of muscle wasting or atrophy. The role of endoplasmic reticulum (ER) stress in muscle atroph..... Read More