Challenges and issues with streptozotocin-induced diabetes - A clinically relevant animal model to understand the diabetes pathogenesis and evaluate therapeutics.

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2016 Jan 25 Others SN Goyal, NM Reddy, KR Patil, KT Nakhate… - Chemico-biological …, 2016 - Elsevier 87

Full Author : ['Goyal, Sameer N', 'Reddy, Navya M', 'Patil, Kalpesh R', 'Nakhate, Kartik T', 'Ojha, Shreesh', 'Patil, Chandragouda R', 'Agrawal, Yogeeta O']
Journal Title : Chemico-biological interactions
Chapter : Section3
Journal Year : 2016
Cited by : 293.0

Streptozotocin (STZ) has been extensively used over the last three decades to induce diabetes in various animal species and to help screen for hypoglycemic drugs. STZ induces clinical features in animals that resemble those associated with diabetes in hum..... Read More

Keywords : ["clinically relevant animal model", "streptozotocininduce diabetes", "evaluate therapeutic", "diabetes pathogenesis", "understand", "issue", "challenge"]
PubMed Link : https://www.sciencedirect.com/science/article/pii/S0009279715301344
Google Scholar Link : https://scholar.google.com/scholar?cites=2670610601526166538&as_sdt=5,32&sciodt=0,32&hl=en&num=20

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Challenges and issues with streptozotocin-induced diabetes - A clinically relevant animal model to understand the diabetes pathogenesis and evaluate therapeutics.