Effect of extract of Pueraria tuberosa on expression of hypoxia inducible factor-1alpha and vascular endothelial growth factor in kidney of diabetic rats.
BACKGROUNDS: Kidney hypoxia represents a unifying mechanism in the pathogenesis of diabetic nephropathy. Hypoxia-induced factor (HIF)-1alpha mediates the metabolic responses of renal hypoxia by modulating the expression of VEGF. In the present study, we i..... Read More