Fabrication of Second Generation Smarter PLGA Based Nanocrystal Carriers for Improvement of Drug Delivery and Therapeutic Efficacy of Gliclazide in Type-2 Diabetes Rat Model.

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2019 Nov 22 Others BP Panda, R Krishnamoorthy, SK Bhattamisra… - Scientific reports, 2019 - Springer 49

Full Author : ['Panda, Bibhu Prasad', 'Krishnamoorthy, Rachna', 'Bhattamisra, Subrat Kumar', 'Shivashekaregowda, Naveen Kumar Hawala', 'Seng, Low Bin', 'Patnaik, Sujata']
Journal Title : Scientific reports
Chapter : Section3
Journal Year : 2019
Cited by : 21.0

Drug delivery and therapeutic challenges of gliclazide, a BCS class II drug used in type 2 diabetes mellitus (T2DM) can be overcome by exploring smarter carriers of second-generation nanocrystals (SGNCs). A combined method of emulsion diffusion, high-pres..... Read More

Keywords : ["second generation smart plga base nanocrystal carrier", "diabetes rat model", "therapeutic efficacy", "drug delivery", "improvement", "gliclazide", "fabrication"]
PubMed Link : https://link.springer.com/content/pdf/10.1038/s41598-019-53996-4.pdf
Google Scholar Link : https://scholar.google.com/scholar?cites=2857573679549519908&as_sdt=5,33&sciodt=0,33&hl=en&num=20

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Fabrication of Second Generation Smarter PLGA Based Nanocrystal Carriers for Improvement of Drug Delivery and Therapeutic Efficacy of Gliclazide in Type-2 Diabetes Rat Model.