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Coumarin-chalcone hybrids targeting insulin receptor: Design, synthesis, anti-diabetic activity, and molecular docking.

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2020 Nov Others SK Konidala, V Kotra, RCSR Danduga, PK Kola - Bioorganic chemistry, 2020 - Elsevier

Full Author : ['Konidala, Sathish Kumar', 'Kotra, Vijay', 'Danduga, Ravi Chandra Sekhara Reddy', 'Kola, Phani Kumar']
Journal Title : Bioorganic chemistry
Chapter : Section3
Journal Year : 2020
Cited by : 19.0

Four series of thirteen new coumarin-chalcone hybrids (DPCU 1-13, DPCT 1-13, DCCU 1-13 and DCCT 1-13) were designed and synthesized using Biginelli synthesis, Pechmann condensation, Acetylation, and Claisen-Schmidt reactions. Synthesized compounds were te..... Read More

Keywords : ["coumarinchalcone hybrid target insulin receptor design synthesis antidiabetic activity", "molecular docking"]
PubMed Link : https://www.sciencedirect.com/science/article/pii/S0045206820315042
Google Scholar Link : https://scholar.google.com/scholar?cites=8380312082062253068&as_sdt=2005&sciodt=0,5&hl=en&num=20