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  • Rapamycin induces autophagy and exacerbates metabolism associated complications in a mouse model of type 1 diabetes.

Rapamycin induces autophagy and exacerbates metabolism associated complications in a mouse model of type 1 diabetes.

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2010 Jan Others Fist_Author_Year_PM

Full Author : ['Zhou, Zhengyu', 'Wu, Shuyan', 'Li, Xinyin', 'Xue, Zhimou', 'Tong, Jian']
Journal Title : Indian journal of experimental biology
Chapter : Section3
Journal Year : 2010
Cited by : Not Available

Type 1 diabetes mellitus (T1DM) is characterized by lack of insulin production as a consequence of massive beta cells destruction. The contributions of autophagy to loss of beta cell mass were not clearly elucidated. Rapamycin is a specific and potent inh.....

Keywords : ["exacerbate metabolism associate complication", "rapamycin induce autophagy", "type diabetes", "mouse model"]