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  • Discovery and development of selective PPAR gamma modulators as safe and effective antidiabetic agents.

Discovery and development of selective PPAR gamma modulators as safe and effective antidiabetic agents.

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2010 Apr Others Fist_Author_Year_PM

Full Author : ['Doshi, Lalit S', 'Brahma, Manoja Kumar', 'Bahirat, Umakant A', 'Dixit, Amol V', 'Nemmani, Kumar V S']
Journal Title : Expert opinion on investigational drugs
Chapter : Section3
Journal Year : 2010
Cited by : Not Available

IMPORTANCE OF THE FIELD: PPARgamma full agonists (pioglitazone and rosiglitazone) are the mainstay drugs for the treatment of type 2 diabetes; however, mechanism-based side effects have limited their full therapeutic potential. In recent years, much progr.....

Keywords : ["selective ppar gamma modulator", "effective antidiabetic agent", "safe", "discovery", "development"]