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  • A mechanistic approach for islet amyloid polypeptide aggregation to develop anti-amyloidogenic agents for type-2 diabetes.

A mechanistic approach for islet amyloid polypeptide aggregation to develop anti-amyloidogenic agents for type-2 diabetes.

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2011 May Others Fist_Author_Year_PM

Full Author : ['Ahmad, Ejaz', 'Ahmad, Aqeel', 'Singh, Saurabh', 'Arshad, Md', 'Khan, Abdul Hameed', 'Khan, Rizwan Hasan']
Journal Title : Biochimie
Chapter : Section3
Journal Year : 2011
Cited by : Not Available

Type-2 diabetes mellitus (DM-2) is a conformational disease involving intrinsically disordered islet amyloid polypeptide (IAPP), in which a structural transition from physiological polypeptide to pathological deposits takes place. Different factors acquir.....

Keywords : ["islet amyloid polypeptide aggregation", "develop antiamyloidogenic agent", "mechanistic approach", "diabetes"]