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  • Metformin mediated reversal of epithelial to mesenchymal transition is triggered by epigenetic changes in E-cadherin promoter.

Metformin mediated reversal of epithelial to mesenchymal transition is triggered by epigenetic changes in E-cadherin promoter.

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2016 Dec Others Fist_Author_Year_PM

Full Author : ['Banerjee, Poulomi', 'Surendran, Harshini', 'Chowdhury, Debabani Roy', 'Prabhakar, Karthik', 'Pal, Rajarshi']
Journal Title : Journal of molecular medicine (Berlin, Germany)
Chapter : Section3
Journal Year : 2016
Cited by : Not Available

Epithelial-mesenchymal transition (EMT) is one of the key biological phenomena behind cancer and metastasis. Clinical studies suggest that patients undergoing metformin therapy are less predisposed to cancer but the underlying mechanism is far from clear......

Keywords : ["metformin mediate reversal", "mesenchymal transition", "epigenetic change", "ecadherin promoter", "trigger", "epithelial"]