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  • Arachidonic acid and lipoxin A4 attenuate alloxan-induced cytotoxicity to RIN5F cells in vitro and type 1 diabetes mellitus in vivo.

Arachidonic acid and lipoxin A4 attenuate alloxan-induced cytotoxicity to RIN5F cells in vitro and type 1 diabetes mellitus in vivo.

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2017 Mar Others Fist_Author_Year_PM

Full Author : ['Gundala, Naveen K V', 'Naidu, Vegi G M', 'Das, Undurti N']
Journal Title : BioFactors (Oxford, England)
Chapter : Section3
Journal Year : 2017
Cited by : Not Available

OBJECTIVE: We studied whether polyunsaturated fatty acids (PUFAs) can protect rat insulinoma (RIN5F) cells against alloxan-induced apoptosis in vitro and type 1 diabetes mellitus (type 1 DM) in vivo and if so, mechanism of this beneficial action. MATERIAL.....

Keywords : ["lipoxin attenuate alloxaninduce cytotoxicity", "type diabetes mellitus", "arachidonic acid", "vivo", "vitro", "cell"]