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- Pathophysiological characteristics of preproinsulin-specific CD8+ T cells in subjects with juvenile-onset and adult-onset type 1 diabetes: A 1-year follow-up study.
Full Author : ['Paul, Mahinder', 'Badal, Darshan', 'Jacob, Neenu', 'Dayal, Devi', 'Kumar, Rakesh', 'Bhansali, Anil', 'Bhadada, Sanjay Kumar', 'Sachdeva, Naresh']
Journal Title : Pediatric diabetes
Chapter : Section3
Journal Year : 2018
Cited by : Not Available
AIMS/HYPOTHESIS: Among the beta-cell associated antigens, preproinsulin (PPI) has been shown to play a key role in the pathogenesis of type 1 diabetes (T1D). PPI-specific autoreactive CD8+ T cells emerge early during beta-cell destruction and persist in p.....
Keywords : ["adultonset type diabetes", "pathophysiological characteristic", "followup study", "subject", "preproinsulinspecific", "juvenileonset", "cell"]