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  • Beneficial effect of recombinant rC1rC2 collagenases on human islet function: Efficacy of low-dose enzymes on pancreas digestion and yield.

Beneficial effect of recombinant rC1rC2 collagenases on human islet function: Efficacy of low-dose enzymes on pancreas digestion and yield.

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2018 Feb Others Fist_Author_Year_PM

Full Author : ['Loganathan, Gopalakrishnan', 'Subhashree, Venugopal', 'Breite, Andrew G', 'Tucker, William W', 'Narayanan, Siddharth', 'Dhanasekaran, Maheswaran', 'Mokshagundam, SriPrakash', 'Green, Michael L', 'Hughes, Michael G', 'Williams, Stuart K', 'Dwulet, Francis E', 'McCarthy, Robert C', 'Balamurugan, Appakalai N']
Journal Title : American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Chapter : Section3
Journal Year : 2018
Cited by : Not Available

A high number of human islets can be isolated by using modern purified tissue dissociation enzymes; however, this requires the use of >20 Wunsch units (WU)/g of pancreas for digestion. Attempts to reduce this dose have resulted in pancreas underdigestion .....

Keywords : ["human islet function efficacy", "recombinant collagenase", "pancreas digestion", "lowdose enzyme", "beneficial effect", "yield"]