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  • Design, synthesis and molecular docking of thiazolidinedione based benzene sulphonamide derivatives containing pyrazole core as potential anti-diabetic agents.

Design, synthesis and molecular docking of thiazolidinedione based benzene sulphonamide derivatives containing pyrazole core as potential anti-diabetic agents.

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2018 Feb Others Fist_Author_Year_PM

Full Author : ['Naim, Mohd Javed', 'Alam, Ozair', 'Alam, Md Jahangir', 'Hassan, Md Quamrul', 'Siddiqui, Nadeem', 'Naidu, V G M', 'Alam, Md Iqbal']
Journal Title : Bioorganic chemistry
Chapter : Section3
Journal Year : 2018
Cited by : Not Available

We herein report the design, synthesis and molecular docking studies of 2,4-thiazolidinedione derivatives containing benzene sulphonyl group which are docked against the Peroxisome Proliferator Activated Receptor (PPARgamma) target. Compound 7p was most e.....

Keywords : ["thiazolidinedione base benzene sulphonamide derivative contain pyrazole core", "potential antidiabetic agent", "molecular docking", "design synthesis"]