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  • The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy.

The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy.

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2018 Feb 12 Others Fist_Author_Year_PM

Full Author : ['Chaurasia, Shyam S', 'Lim, Rayne R', 'Parikh, Bhav H', 'Wey, Yeo Sia', 'Tun, Bo Bo', 'Wong, Tien Yin', 'Luu, Chi D', 'Agrawal, Rupesh', 'Ghosh, Arkasubhra', 'Mortellaro, Alessandra', 'Rackoczy, Elizabeth', 'Mohan, Rajiv R', 'Barathi, Veluchamy A']
Journal Title : Scientific reports
Chapter : Section3
Journal Year : 2018
Cited by : Not Available

Diabetic retinopathy (DR) is a retinal microvascular disease characterized by inflammatory and angiogenic pathways. In this study, we evaluated NLRP3 inflammasome in a double transgenic mouse model, Akimba (Ins2 (Akita) xVEGF(+/-)), which demonstrates hyp.....

Keywords : ["inflammasome may contribute", "pathologic neovascularization", "diabetic retinopathy", "advanced stage"]