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Structural insights into suppressor of cytokine signaling 1 protein- identification of new leads for type 2 diabetes mellitus.

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2018 Jul Others Fist_Author_Year_PM

Full Author : ['Dumpati, Ramakrishna', 'Ramatenki, Vishwanath', 'Vadija, Rajender', 'Vellanki, Santhiprada', 'Vuruputuri, Uma']
Journal Title : Journal of molecular recognition : JMR
Chapter : Section3
Journal Year : 2018
Cited by : Not Available

The study considers the Suppressor of cytokine signaling 1 (SOCS1) protein as a novel Type 2 diabetes mellitus (T2DM) drug target. T2DM in human beings is also triggered by the over expression of SOCS proteins. The SOCS1 acts as a ubiquitin ligase (E3), d.....

Keywords : ["cytokine signal protein identification", "type diabetes mellitus", "structural insight", "new lead", "suppressor"]