RSSDI Repository, Complications of Diabetes Demonstration RSSDI Repository, Complications of Diabetes Demonstration

Have a Question?

If you have any question you can ask below or enter what you are looking for!

  • Home/
  • Article /
  • Activation of GSK3beta/beta-TrCP axis via PHLPP1 exacerbates Nrf2 degradation leading to impairment in cell survival pathway during diabetic nephropathy.

Activation of GSK3beta/beta-TrCP axis via PHLPP1 exacerbates Nrf2 degradation leading to impairment in cell survival pathway during diabetic nephropathy.

Add to Collection
2018 May 20 Others Fist_Author_Year_PM

Full Author : ['Mathur, Alpana', 'Pandey, Vivek Kumar', 'Kakkar, Poonam']
Journal Title : Free radical biology & medicine
Chapter : Section3
Journal Year : 2018
Cited by : Not Available

NF-E2 p45-related factor 2 (Nrf2), is a major redox sensitive transcription factor that plays an essential role in regulating glucose metabolism. Inactivation of Nrf2 has been associated with diabetic complications however, mechanisms warranting Nrf2 supp.....

Keywords : ["axis via exacerbate degradation lead", "cell survival pathway", "diabetic nephropathy", "impairment", "activation"]