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  • Combination of APD668, a G protein-coupled receptor 119 agonist with linagliptin, a DPPIV inhibitor, prevents progression of steatohepatitis in a murine model of non-alcoholic steatohepatitis with diabetes.

Combination of APD668, a G protein-coupled receptor 119 agonist with linagliptin, a DPPIV inhibitor, prevents progression of steatohepatitis in a murine model of non-alcoholic steatohepatitis with diabetes.

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2019 Mar Others Fist_Author_Year_PM

Full Author : ['Bahirat, Umakant Ashok', 'Talwar, Rashmi', 'Shenoy, Rekha Raghuveer', 'Nemmani, Kumar V S', 'Goel, Rajan Naresh']
Journal Title : Medical molecular morphology
Chapter : Section3
Journal Year : 2019
Cited by : Not Available

Non-alcoholic steatohepatitis (NASH) is characterized by the presence of hepatic steatosis, oxidative stress, inflammation, and hepatocyte injury with or without fibrosis. In this study, we explored the effect of APD668, a GPR119 agonist alone or in combi.....

Keywords : ["g proteincouple receptor agonist", "dppiv inhibitor prevent progression", "murine model", "nonalcoholic steatohepatitis", "steatohepatitis", "linagliptin", "diabetes", "combination"]