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  • Pharmacological evaluation of novel PKR inhibitor indirubin-3-hydrazone in-vitro in cardiac myocytes and in-vivo in wistar rats.

Pharmacological evaluation of novel PKR inhibitor indirubin-3-hydrazone in-vitro in cardiac myocytes and in-vivo in wistar rats.

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2018 Sep 15 Others Fist_Author_Year_PM

Full Author : ['Udumula, Mary Priyanka', 'Bhat, Audesh', 'Mangali, Sureshbabu', 'Kalra, Jaspreet', 'Dhar, Indu', 'Sriram, Dharamrajan', 'Dhar, Arti']
Journal Title : Life sciences
Chapter : Section3
Journal Year : 2018
Cited by : Not Available

AIMS: Double stranded protein kinase R cellular response is associated with various stress signals such as nutrients, endoplasmic stress, cytokines and mechanical stress. Increased PKR activity has been observed under diabetic and cardiovascular disease c.....

Keywords : ["novel pkr inhibitor invitro", "wistar rat", "pharmacological evaluation", "cardiac myocyte", "invivo"]