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  • EGFR tyrosine kinase inhibition decreases cardiac remodeling and SERCA2a/NCX1 depletion in streptozotocin induced cardiomyopathy in C57/BL6 mice.

EGFR tyrosine kinase inhibition decreases cardiac remodeling and SERCA2a/NCX1 depletion in streptozotocin induced cardiomyopathy in C57/BL6 mice.

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2018 Oct 1 Others Fist_Author_Year_PM

Full Author : ['Shah, Sadia', 'Akhtar, Md Sayeed', 'Hassan, Md Quamrul', 'Akhtar, Mohd', 'Paudel, Yam Nath', 'Najmi, Abul Kalam']
Journal Title : Life sciences
Chapter : Section3
Journal Year : 2018
Cited by : Not Available

AIM: Epidermal growth factor receptor (EGFR) related reactive oxygen species (ROS) generation results in myocardial damage. We aimed to investigate the role of gefitinib (EGFR-tyrosine kinase inhibitor) in diabetic cardiomyopathy (DbCM). METHOD: DbCM was .....

Keywords : ["egfr tyrosine kinase inhibition decrease cardiac remodeling", "streptozotocin induce cardiomyopathy", "mouse", "depletion"]