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  • Insulin adsorption onto zinc oxide nanoparticle mediates conformational rearrangement into amyloid-prone structure with enhanced cytotoxic propensity.

Insulin adsorption onto zinc oxide nanoparticle mediates conformational rearrangement into amyloid-prone structure with enhanced cytotoxic propensity.

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2019 Jan Others Fist_Author_Year_PM

Full Author : ['Asthana, Shreyasi', 'Hazarika, Zaved', 'Nayak, Parth Sarathi', 'Roy, Jyoti', 'Jha, Anupam Nath', 'Mallick, Bibekanand', 'Jha, Suman']
Journal Title : Biochimica et biophysica acta. General subjects
Chapter : Section3
Journal Year : 2019
Cited by : Not Available

BACKGROUND: Injection localized amyloidosis is one of the most prevalent disorders in type II diabetes mellitus (TIIDM) patients relying on insulin injections. Previous studies have reported that nanoparticles can play a role in the amyloidogenic process .....

Keywords : ["insulin adsorption onto zinc oxide nanoparticle mediate conformational rearrangement", "enhanced cytotoxic propensity", "amyloidprone structure"]