RSSDI Repository, Complications of Diabetes Demonstration RSSDI Repository, Complications of Diabetes Demonstration

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Characterization of proinsulin-specific regulatory T cells in type 1 diabetes at different ages of onset.

BACKGROUND AND OBJECTIVES: Regulatory T cells (Tregs) play an important role in maintaining tolerance to self-antigens. Defects in the frequency and function of polyclonal Tregs have been reported in type 1 diabetes (T1D). However, characteristics of proi.....