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  • Differential methylation of the type 2 diabetes susceptibility locus KCNQ1 is associated with insulin sensitivity and is predicted by CpG site specific genetic variation.

Differential methylation of the type 2 diabetes susceptibility locus KCNQ1 is associated with insulin sensitivity and is predicted by CpG site specific genetic variation.

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2019 Feb Others Fist_Author_Year_PM

Full Author : ['Shah, Ushma J', 'Xie, Weijia', 'Flyvbjerg, Allan', 'Nolan, John J', 'Hojlund, Kurt', 'Walker, Mark', 'Relton, Caroline L', 'Elliott, Hannah R']
Journal Title : Diabetes research and clinical practice
Chapter : Section3
Journal Year : 2019
Cited by : Not Available

AIMS: Epigenetic mechanisms regulate gene expression and may influence the pathogenesis of type 2 diabetes through the loss of insulin sensitivity. The aims of this study were to measure variation in DNA methylation at the type 2 diabetes locus KCNQ1 and .....

Keywords : ["cpg site specific genetic variation", "type diabetes susceptibility locus", "insulin sensitivity", "differential methylation", "predict", "associate"]