RSSDI Repository, Complications of Diabetes Demonstration RSSDI Repository, Complications of Diabetes Demonstration

Have a Question?

If you have any question you can ask below or enter what you are looking for!

  • Home/
  • Article /
  • eIF5A inhibition influences T cell dynamics in the pancreatic microenvironment of the humanized mouse model of Type 1 Diabetes.

eIF5A inhibition influences T cell dynamics in the pancreatic microenvironment of the humanized mouse model of Type 1 Diabetes.

Add to Collection
2019 Feb 7 Others Fist_Author_Year_PM

Full Author : ['Imam, Shahnawaz', 'Prathibha, R', 'Dar, Pervaiz', 'Almotah, Khalil', 'Al-Khudhair, Ahmed', 'Hasan, Syed Abdul-Moiz', 'Salim, Nancy', 'Jilani, Talha Naser', 'Mirmira, Raghavendra G', 'Jaume, Juan Carlos']
Journal Title : Scientific reports
Chapter : Section3
Journal Year : 2019
Cited by : Not Available

We have developed a transgenic mouse model of Type 1 Diabetes (T1D) in which human GAD65 is expressed in pancreatic beta-cells, and human MHC-II is expressed on antigen presenting cells. Induced GAD65 antigen presentation activates T-cells, which initiate.....

Keywords : ["humanize mouse model", "type diabetes", "pancreatic microenvironment", "inhibition influence", "cell dynamics"]