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  • Protection of Primary Dopaminergic Midbrain Neurons Through Impact of Small Molecules Using Virtual Screening of GPR139 Supported by Molecular Dynamic Simulation and Systems Biology.

Protection of Primary Dopaminergic Midbrain Neurons Through Impact of Small Molecules Using Virtual Screening of GPR139 Supported by Molecular Dynamic Simulation and Systems Biology.

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2019 Jun Others Fist_Author_Year_PM

Full Author : ['Kaushik, Aman Chandra', 'Gautam, Deeksha', 'Nangraj, Asma Sindhoo', 'Wei, Dong-Qing', 'Sahi, Shakti']
Journal Title : Interdisciplinary sciences, computational life sciences
Chapter : Section3
Journal Year : 2019
Cited by : Not Available

INTRODUCTION: GPCR share a common structural feature, i.e., the presence of seven trans-membrane helices having three intracellular and three extracellular loops. The carboxyl terminal is intracellular whereas amino terminal is extracellular. Various conf.....

Keywords : ["small molecule use virtual screening", "primary dopaminergic midbrain neuron", "molecular dynamic simulation", "system biology", "support", "protection", "impact"]