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  • Induced pluripotent stem cell macrophages present antigen to proinsulin-specific T cell receptors from donor-matched islet-infiltrating T cells in type 1 diabetes.

Induced pluripotent stem cell macrophages present antigen to proinsulin-specific T cell receptors from donor-matched islet-infiltrating T cells in type 1 diabetes.

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2019 Dec Others Fist_Author_Year_PM

Full Author : ['Joshi, Kriti', 'Elso, Colleen', 'Motazedian, Ali', 'Labonne, Tanya', 'Schiesser, Jacqueline V', 'Cameron, Fergus', 'Mannering, Stuart I', 'Elefanty, Andrew G', 'Stanley, Edouard G']
Journal Title : Diabetologia
Chapter : Section3
Journal Year : 2019
Cited by : Not Available

AIMS/HYPOTHESIS: Type 1 diabetes is an autoimmune disorder characterised by loss of insulin-producing beta cells of the pancreas. Progress in understanding the cellular and molecular mechanisms underlying the human disease has been hampered by a dearth of.....

Keywords : ["induce pluripotent stem cell macrophage present antigen", "cell receptor", "type diabetes", "donormatche isletinfiltrate", "cell", "proinsulinspecific"]