Efonidipine Exerts Cerebroprotective Effect by Down-regulation of TGF-beta/SMAD-2-Dependent Signaling Pathway in Diabetic Rats.
Calcium overload and hyperglycemia are risks of stroke onset in diabetics. Our study was designed to elucidate the beneficial role of calcium channel blockers by targeting voltage-gated calcium channels in diabetes-associated cerebrovascular complications.....