P2X7 receptor in multifaceted cellular signalling and its relevance as a potential therapeutic target in different diseases.
P2X7 receptor, a purinergic receptor family member, is abundantly expressed on many cells, including immune, muscle, bone, neuron, and glia. It acts as an ATP-activated cation channel that permits the influx of Ca(2+), Na(+) and efflux of K(+) ions. The P.....