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  • Fetuin-A secretion from beta-cells leads to accumulation of macrophages in islets, aggravates inflammation and impairs insulin secretion.

Fetuin-A secretion from beta-cells leads to accumulation of macrophages in islets, aggravates inflammation and impairs insulin secretion.

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2021 Nov 1 Others Fist_Author_Year_PM

Full Author : ['Mukhuty, Alpana', 'Fouzder, Chandrani', 'Kundu, Rakesh']
Journal Title : Journal of cell science
Chapter : Section3
Journal Year : 2021
Cited by : Not Available

Elevated fetuin-A levels, chemokines and islet-resident macrophages are crucial factors associated with obesity-mediated type 2 diabetes (T2D). Here, the aim of the study was to investigate the effect of MIN6 (a mouse insulinoma cell line)-derived fetuin-.....

Keywords : ["islet aggravate inflammation", "impairs insulin secretion", "fetuina secretion", "betacell lead", "macrophage", "accumulation"]