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  • Identification of Selective PPAR-gamma Modulators by Combining Pharmacophore Modeling, Molecular Docking, and Adipogenesis Assay.

Identification of Selective PPAR-gamma Modulators by Combining Pharmacophore Modeling, Molecular Docking, and Adipogenesis Assay.

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2023 Feb Others Fist_Author_Year_PM

Full Author : ['Li, Yunwei', 'Ks, Nagashree', 'Byran, Gowramma', 'Krishnamurthy, Praveen Thaggikuppe']
Journal Title : Applied biochemistry and biotechnology
Chapter : Section3
Journal Year : 2023
Cited by : Not Available

The clinically used glitazones (rosiglitazone and pioglitazone) for type 2 diabetes mellitus therapy have been linked to serious side effects such as fluid retention, congestive heart failure, weight gain, bone loss, and an increased risk of bladder cance.....

Keywords : ["combine pharmacophore model molecular docking", "selective ppargamma modulator", "adipogenesis assay", "identification"]