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  • Regulation of peroxiredoxin-3 gene expression under basal and hyperglycemic conditions: Key roles for transcription factors Sp1, CREB and NF-kappaB.

Regulation of peroxiredoxin-3 gene expression under basal and hyperglycemic conditions: Key roles for transcription factors Sp1, CREB and NF-kappaB.

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2023 Jun Others Fist_Author_Year_PM

Full Author : ['Arkat, Silpa', 'Poovitha, Sundar', 'Vijayakumar, Anupama', 'Dhat, Rohini', 'Sitasawad, Sandhya L', 'Mahapatra, Nitish R']
Journal Title : Biochimica et biophysica acta. Molecular basis of disease
Chapter : Section3
Journal Year : 2023
Cited by : Not Available

Peroxiredoxin-3 (Prx-3), a thioredoxin-dependent peroxidase located exclusively in the mitochondrial matrix, catalyses peroxides/peroxinitrites. Altered levels of Prx-3 is associated with diabetic cardiomyopathy (DCM). However, molecular mechanisms of Prx.....

Keywords : ["hyperglycemic condition key role", "transcription factor creb", "gene expression", "regulation", "nfkappab", "basal"]