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  • Sphingosine 1 phosphate lyase inhibition rescues cognition in diabetic mice by promoting anti-inflammatory microglia.

Sphingosine 1 phosphate lyase inhibition rescues cognition in diabetic mice by promoting anti-inflammatory microglia.

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2023 May 28 Others Fist_Author_Year_PM

Full Author : ['Sood, Anika', 'Fernandes, Valencia', 'Preeti, Kumari', 'Khatri, Dharmendra Kumar', 'Singh, Shashi Bala']
Journal Title : Behavioural brain research
Chapter : Section3
Journal Year : 2023
Cited by : Not Available

Sphingosine-1-phosphate (S1P) is emerging as a crucial sphingolipid modulating neuroinflammation and cognition. S1P levels in the brain have been found to be decreased in cognitive impairment. S1P lyase (S1PL) is the key enzyme in metabolizing S1P and has.....

Keywords : ["sphingosine phosphate lyase inhibition rescue cognition", "promote antiinflammatory microglia", "diabetic mouse"]