RSSDI Repository, Complications of Diabetes Demonstration RSSDI Repository, Complications of Diabetes Demonstration

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Effects of vanadyl sulphate on glucose homeostasis in severe diabetes induced by streptozotocin in rats.

Rats made severely diabetic by an i.v. injection of 50-55 mg/kg streptozotocin (STZ), 15 days later showed blood glucose > 500 mg/dl, quadrupled daily water intake and plasma insulin of 14 +/- 3 microU/ml, about 25 per cent that of normal rats. Subsequent.....