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  • Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening.

Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening.

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2005 Oct Others Fist_Author_Year_PM

Full Author : ['Srinivasan, K', 'Viswanad, B', 'Asrat, Lydia', 'Kaul, C L', 'Ramarao, P']
Journal Title : Pharmacological research
Chapter : Section3
Journal Year : 2005
Cited by : Not Available

The objective of the present study was to develop a rat model that replicates the natural history and metabolic characteristics of human type 2 diabetes and is also suitable for pharmacological screening. Male Sprague-Dawley rats (160-180 g) were divided .....

Keywords : ["lowdose streptozotocintreated rat", "type diabetes", "pharmacological screening", "highfat dietfe", "model", "combination"]