The hypoglycaemic activity of fenugreek seed extract is mediated through the stimulation of an insulin signalling pathway.
The in vivo hypoglycaemic activity of a dialysed fenugreek seed extract (FSE) was studied in alloxan (AXN)-induced diabetic mice and found to be comparable to that of insulin (1.5 U kg(-1)). FSE also improved intraperitoneal glucose tolerance in normal mi.....