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  • Synthesis and antihyperglycemic activity of novel N-acyl-2-arylethylamines and N-acyl-3-coumarylamines.

Synthesis and antihyperglycemic activity of novel N-acyl-2-arylethylamines and N-acyl-3-coumarylamines.

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2008 Apr 1 Others Fist_Author_Year_PM

Full Author : ['Dwivedi, Atma P', 'Kumar, Shailesh', 'Varshney, Vandana', 'Singh, Amar B', 'Srivastava, Arvind K', 'Sahu, Devi P']
Journal Title : Bioorganic & medicinal chemistry letters
Chapter : Section3
Journal Year : 2008
Cited by : Not Available

A series of novel N-acyl-2-arylethylamines and N-acyl-3-coumarylamines were synthesized and evaluated for their antihyperglycemic activity. Compounds 3g and 6d exhibited lowering of postprandial plasma glucose by 30.7%, 23.3% in SLM and 25.6%, 25.4% in ST.....

Keywords : ["antihyperglycemic activity", "synthesis", "novel"]