Possible role of spleen-derived factors, vanilloid receptors and calcitonin gene-related peptide in diabetes induced hyperalgesia in mice.
The present study was designed to investigate a possible role of vanilloid receptors, CGRP and spleen in the induction of diabetes induced hyperalgesia in mice. Tail flick latency, an index of hyperalgesia, was assessed using analgesiometer. Serum nitrite.....