Synthesis and antihyperglycemic activity of 2-(substituted phenyl)-3-[4-(1-naphthyl)-1,3-thiazol-2-yl] amino-4-oxo-1,3-thiazolidin-5-ylacetic acid derivatives.
The title compounds were prepared by brominating 1-acetylnaphthalene in chloroform followed by condensation with substituted benzaldehyde thiosemicarbazones using ethanol to get 4-naphthalen-1-yl-2-2-[(substituted phenyl)methylidene]hydrazino-1,3-thiazole.....