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  • Design and synthesis of 3,5-diarylisoxazole derivatives as novel class of anti-hyperglycemic and lipid lowering agents.

Design and synthesis of 3,5-diarylisoxazole derivatives as novel class of anti-hyperglycemic and lipid lowering agents.

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2009 Jul 15 Others Fist_Author_Year_PM

Full Author : ['Kumar, Atul', 'Maurya, Ram Awatar', 'Sharma, Siddharth', 'Ahmad, Pervez', 'Singh, A B', 'Tamrakar, A K', 'Srivastava, Arvind K']
Journal Title : Bioorganic & medicinal chemistry
Chapter : Section3
Journal Year : 2009
Cited by : Not Available

We have designed 1,3-disubstituted-5-membered heteroaromatic ring system as a common core motif from known anti-hyperglycemic agents. Designed compounds were synthesized and screened for in vivo anti-hyperglycemic activity in sucrose loaded model (SLM), s.....

Keywords : ["lipid lowering agent", "novel class", "synthesis", "design", "derivative", "antihyperglycemic"]