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  • Pioglitazone, a PPAR-gamma ligand inhibited the nicotinamide-streptozotocin induced sperm abnormalities in type-2 diabetic Wistar rats.

Pioglitazone, a PPAR-gamma ligand inhibited the nicotinamide-streptozotocin induced sperm abnormalities in type-2 diabetic Wistar rats.

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2010 Jul Others Fist_Author_Year_PM

Full Author : ['Rabbani, Syed Imam', 'Devi, Kshama', 'Khanam, Salma']
Journal Title : Pakistan journal of pharmaceutical sciences
Chapter : Section3
Journal Year : 2010
Cited by : Not Available

Oxidative stress due to chronic hyperglycemia is known to cause infertility in diabetic patients. Pioglitazone (PIO), a PPAR-gamma ligand is known to possess the antioxidant property however, its role on the oxidative stress mediated germinal damage in Ty.....

Keywords : ["nicotinamidestreptozotocin induce sperm abnormality", "ppargamma ligand inhibit", "diabetic wistar rat", "pioglitazone"]