Muscarinic M(1), M(3) receptor modulation in the corpus striatum of streptozotocin induced diabetic rats as a function of age.
OBJECTIVES: In this study we have investigated muscarinic M(1), M(3) receptor kinetics and the functional role of IP3 and cGMP in the corpus striatum of both young and old diabetic and insulin-treated diabetic rats. METHODS: Radioreceptor binding assays w.....