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  • Influence of atorvastatin on the pharmacokinetics and pharmacodynamics of glyburide in normal and diabetic rats.

Influence of atorvastatin on the pharmacokinetics and pharmacodynamics of glyburide in normal and diabetic rats.

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2011 Feb 14 Others Fist_Author_Year_PM

Full Author : ['Neerati, Prasad', 'Gade, Jyothsna']
Journal Title : European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Chapter : Section3
Journal Year : 2011
Cited by : Not Available

Atorvastatin is a selective HMG-CoA reductase competitive inhibitor, used for the treatment of hyperlipidaemia. It is metabolized by CYP 3A4 and 3A5 isoenzymes in liver. It also has moderate inhibition on metabolizing enzymes like CYP 2C9, 2D6 and 3A4. He.....

Keywords : ["diabetic rat", "pharmacokinetic", "pharmacodynamic", "normal", "influence", "glyburide", "atorvastatin"]