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Pigment epithelium-derived factor inhibits advanced glycation end-products-induced cytotoxicity in retinal pericytes.

AIM: This study investigated the effects of pigment epithelium-derived factor (PEDF) on advanced glycation end-product (AGE)-induced cytotoxicity in porcine retinal pericytes and the signalling mechanism involved. METHODS: Retinal pericytes were isolated .....